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KMID : 0356719970130010023
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Journal of the Korean Society of Coloproctology
1997 Volume.13 No. 1 p.23 ~ p.30
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Flow Cytometric DNA Analysis in Colorectal Cancer and Its Relationship to Clinicopathological Features and Prognosis
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Choi Dong-Ho
Son Tae-Sung
Park Young-Seok
Baik Hong-Kyu
Nam Young-Soo
Jun Kyu-Young
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Abstract
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DNA flow cytometric analysis was performed on 42 colorectal cancers. DNA ploidy was diploid in 19 and aneuploid in 23 cases. There was no significant correlation between DNA ploidy and clinicopathological features such as primary site, histologic type, depth of invasion, lymph node metastasis, peritoneal seedings, lymphatic invasion and vascular invasion. In aneuploid group, which was divided into two groups, by the value of DNA index, there was no differences between two groups in prognosis and clinocoPathological features. Cumulative survival rates appeared to be more favorable in
patients with aneuploid tumors than patients with diploid tumors, but the difference was not statistically significant.
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KEYWORD
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Flow Cytometry
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